BAIT

LST-3

CELE_Y37A1B.1
Protein LST-3
GO Process (3)
GO Function (0)
GO Component (0)

Gene Ontology Biological Process

Caenorhabditis elegans
PREY

UNC-108

CELE_F53F10.4, unc-67, rab-2, F53F10.4
unc-108 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; unc-108 function is required in neurons for normal locomotion; unc-108 also functions in the removal of apoptotic cells, specifically it functions in engulfing cells for the recruitment and fusion of the lysosome to the phagosome; unc-108 is expressed in neurons and in engulfing cells.
Caenorhabditis elegans

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing.

Lugano DI, Barrett LN, Chaput D, Park MA, Westerheide SD

The Cell Division Cycle and Apoptosis Regulator (CCAR) protein family members have recently emerged as regulators of alternative splicing and transcription, as well as having other key physiological functions. For example, mammalian CCAR2/DBC1 forms a complex with the zinc factor protein ZNF326 to integrate alternative splicing with RNA polymerase II transcriptional elongation in AT-rich regions of the DNA. Additionally, Caenorhabditis ... [more]

RNA Biol Jan. 01, 2024; 21(1);1-11 [Pubmed: 38126797]

Throughput

  • High Throughput

Curated By

  • BioGRID