BAIT

LST-3

CELE_Y37A1B.1
Protein LST-3
GO Process (3)
GO Function (0)
GO Component (0)

Gene Ontology Biological Process

Caenorhabditis elegans
PREY

SEC-23

CELE_Y113G7A.3, Y113G7A.3
sec-23 encodes a component of COPII (coat protein complex II)-coated vesicles orthologous to Saccharomyces cerevisiae Sec23p; by homology, SEC-23 is predicted to be involved in endoplasmic reticulum (ER)-to-Golgi transport; loss of sec-23 activity results in defects in oogenesis, morphogenesis, and extracellular matrix secretion; a SEC-23::GFP fusion protein localizes to the apical region of the endoplasmic reticulum of hypodermal cells, consistent with localization to endoplasmic reticulum exit sites.
Caenorhabditis elegans

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing.

Lugano DI, Barrett LN, Chaput D, Park MA, Westerheide SD

The Cell Division Cycle and Apoptosis Regulator (CCAR) protein family members have recently emerged as regulators of alternative splicing and transcription, as well as having other key physiological functions. For example, mammalian CCAR2/DBC1 forms a complex with the zinc factor protein ZNF326 to integrate alternative splicing with RNA polymerase II transcriptional elongation in AT-rich regions of the DNA. Additionally, Caenorhabditis ... [more]

RNA Biol Jan. 01, 2024; 21(1);1-11 [Pubmed: 38126797]

Throughput

  • High Throughput

Curated By

  • BioGRID