BAIT

IGF2BP3

CT98, IMP-3, IMP3, KOC, KOC1, VICKZ3
insulin-like growth factor 2 mRNA binding protein 3
Human Papilloma Virus (HPV) Project
Homo sapiens
PREY

CIT

CRIK, STK21
citron rho-interacting serine/threonine kinase
Cell Cycle - Mitotic Spindle Assembly Project
GO Process (4)
GO Function (3)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Publication

CircNFATC3 promotes the proliferation of gastric cancer through binding to IGF2BP3 and restricting its ubiquitination to enhance CCND1 mRNA stability.

Yang F, Ma Q, Huang B, Wang X, Pan X, Yu T, Ran L, Jiang S, Li H, Chen Y, Liu Y, Liang C, Ren J, Zhang Y, Wang S, Li W, Xiao B

Insulin like growth factor II mRNA binding protein 3 (IGF2BP3) is an RNA binding protein with multiple roles in regulation of gene expression at the post-transcriptional level and is implicated in tumorigenesis and progression of numerous cancers including gastric cancer (GC). Circular RNAs (circRNAs) are a diverse endogenous noncoding RNA population that have important regulatory roles in cancer. However, circRNAs that ... [more]

J Transl Med Jun. 20, 2023; 21(1);402 [Pubmed: 37340423]

Throughput

  • High Throughput

Additional Notes

  • Hit is circular RNA

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
CIT IGF2BP3
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High-BioGRID
-

Curated By

  • BioGRID