ELM1
Gene Ontology Biological Process
- axial cellular bud site selection [TAS]
- budding cell bud growth [IMP]
- cell morphogenesis [IMP]
- cytokinesis checkpoint [TAS]
- glucose metabolic process [IGI, IMP]
- positive regulation of protein autophosphorylation [IDA, IMP]
- protein autophosphorylation [IDA, IMP]
- protein phosphorylation [IDA, IGI]
- pseudohyphal growth [IMP]
- response to drug [IMP]
- response to osmotic stress [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
HSL1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
Regulation of cytokinesis by the Elm1 protein kinase in Saccharomyces cerevisiae.
A Saccharomyces cerevisiae mutant unable to grow in a cdc28-1N background was isolated and shown to be affected in the ELM1 gene. Elm1 is a protein kinase, thought to be a negative regulator of pseudo-hyphal growth. We show that Cdc11, one of the septins, is delocalised in the mutant, indicating that septin localisation is partly controlled by Elm1. Moreover, we ... [more]
Throughput
- Low Throughput
Ontology Terms
- inviable (APO:0000112)
Additional Notes
- HSL1/GIN4/KCC4/ELM1 quadruple mutants show synthetic lethality
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ELM1 HSL1 | Phenotypic Suppression Phenotypic Suppression A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 1029479 | |
| ELM1 HSL1 | Synthetic Rescue Synthetic Rescue A genetic interaction is inferred when mutations or deletions of one gene rescues the lethality or growth defect of a strain mutated or deleted for another gene. | Low | - | BioGRID | 344078 | |
| ELM1 HSL1 | Synthetic Rescue Synthetic Rescue A genetic interaction is inferred when mutations or deletions of one gene rescues the lethality or growth defect of a strain mutated or deleted for another gene. | Low | - | BioGRID | 260328 | |
| ELM1 HSL1 | Synthetic Rescue Synthetic Rescue A genetic interaction is inferred when mutations or deletions of one gene rescues the lethality or growth defect of a strain mutated or deleted for another gene. | Low | - | BioGRID | 511122 |
Curated By
- BioGRID