ARG2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CLB5
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IEP, IMP]
- G2/M transition of mitotic cell cycle [IEP, IMP]
- positive regulation of DNA replication [IMP]
- positive regulation of spindle pole body separation [IGI]
- premeiotic DNA replication [IGI, IMP]
- regulation of cyclin-dependent protein serine/threonine kinase activity [IDA]
- spindle assembly [IGI, IMP]
Gene Ontology Molecular Function
Phenotypic Enhancement
A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.
Publication
MRC1-dependent scaling of the budding yeast DNA replication timing program.
We describe the DNA replication timing programs of 14 yeast mutants with an extended S phase identified by a novel genome-wide screen. These mutants are associated with the DNA replication machinery, cell-cycle control, and dNTP synthesis and affect different parts of S phase. In 13 of the mutants, origin activation time scales with the duration of S phase. A limited ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: cell cycle progression in s phase (APO:0000266)
Additional Notes
- Cell cycle arrest is aggravated in the double mutant
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CLB5 ARG2 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 430804 |
Curated By
- BioGRID