KIN1
Gene Ontology Biological Process
Gene Ontology Cellular Component
PMP1
Gene Ontology Biological Process
- cellular chloride ion homeostasis [IMP]
- cellular response to salt stress [IMP]
- inactivation of MAPK activity [IDA]
- peptidyl-tyrosine dephosphorylation [IDA]
- peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [IDA]
- positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion [IMP]
- protein dephosphorylation [IDA]
- regulation of cell morphogenesis [IMP]
- regulation of mitotic cytokinesis [IMP]
- regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion [IMP]
Gene Ontology Molecular Function
Phenotypic Enhancement
A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.
Publication
Kin1 is a plasma membrane-associated kinase which regulates the cell surface in fission yeast.
ABSTRACT Cell morphogenesis is a complex process that depends on cytoskeleton and membrane organization, intracellular signalling and vesicular trafficking. The rod shape of the fission yeast Schizosaccharomyces pombe and the availability of powerful genetic tools make this species an excellent model to study cell morphology. Here we have investigated the function of the conserved Kin1 kinase. Kin1-GFP associates dynamically with ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: protein/peptide modification (APO:0000131)
- phenotype: endomembrane system morphology (APO:0000303)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| KIN1 PMP1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -3.3757 | BioGRID | 774829 | |
| KIN1 PMP1 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 816325 | |
| PMP1 KIN1 | Synthetic Growth Defect Synthetic Growth Defect A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell. | Low | - | BioGRID | 448502 | |
| KIN1 PMP1 | Synthetic Growth Defect Synthetic Growth Defect A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell. | Low | - | BioGRID | 816717 |
Curated By
- BioGRID