BAIT
KR
CG3340, Dm-Kr, Dmel\CG3340, If, Dmel_CG3340
Kruppel
GO Process (17)
GO Function (5)
GO Component (1)
Gene Ontology Biological Process
- Malpighian tubule bud morphogenesis [IGI]
- Malpighian tubule morphogenesis [NAS, TAS]
- axon guidance [IMP]
- chromatin silencing [IMP]
- compound eye development [IMP]
- ganglion mother cell fate determination [TAS]
- muscle organ development [TAS]
- negative regulation of gene expression [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA, TAS]
- negative regulation of transcription, DNA-templated [IDA]
- neuroblast fate determination [IEP, IMP]
- regulation of development, heterochronic [NAS, TAS]
- regulation of hemocyte proliferation [IMP]
- trunk segmentation [TAS]
- ventral cord development [NAS]
- wing disc development [IGI]
- zygotic determination of anterior/posterior axis, embryo [NAS, TAS]
Gene Ontology Molecular Function- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- chromatin binding [NAS]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA, NAS]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- chromatin binding [NAS]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA, NAS]
Drosophila melanogaster
PREY
CTBP
0256/16, 256/16, BcDNA:GH07572, CG7583, Dm-CtBP, Dmel\CG7583, EP(3)3528, G9, RE01030, RE61183, dCtBP, l(3)03463, l(3)03464, l(3)87DE, l(3)G9, Dmel_CG7583
C-terminal Binding Protein
GO Process (11)
GO Function (7)
GO Component (1)
Gene Ontology Biological Process
- Wnt signaling pathway [IGI]
- chaeta development [IMP]
- embryonic development via the syncytial blastoderm [IMP]
- negative regulation of transcription from RNA polymerase II promoter [TAS]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- positive regulation of JAK-STAT cascade [IMP]
- regulation of Wnt signaling pathway [IMP]
- regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of transcription, DNA-templated [IMP]
- sensory organ precursor cell fate determination [IMP]
- wing disc development [IMP]
Gene Ontology Molecular Function
Drosophila melanogaster
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
SAP18 promotes Krueppel-dependent transcriptional repression by enhancer-specific histone deacetylation.
Body pattern formation during early embryogenesis of Drosophila melanogaster relies on a zygotic cascade of spatially restricted transcription factor activities. The gap gene Krueppel ranks at the top level of this cascade. It encodes a C2H2 zinc finger protein that interacts directly with cis-acting stripe enhancer elements of pair rule genes, such as even skipped and hairy, at the next ... [more]
J. Biol. Chem. Jan. 30, 2009; 284(5);3012-20 [Pubmed: 19049982]
Throughput
- Low Throughput
Related interactions
Curated By
- BioGRID