CLP1
Gene Ontology Biological Process
- cellular response to DNA damage stimulus [IMP]
- chromosome passenger complex localization to spindle midzone [IMP]
- cytokinesis after mitosis checkpoint [IMP]
- cytokinesis checkpoint [IGI]
- mitotic actomyosin contractile ring maintenance [IGI, IMP]
- negative regulation of G2/M transition of mitotic cell cycle [IMP]
- negative regulation of cyclin-dependent protein serine/threonine kinase activity [IGI]
- negative regulation of protein kinase activity [IMP]
- positive regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation [IMP]
- positive regulation of septation initiation signaling [IGI]
- regulation of exit from mitosis [IMP]
- regulation of mitotic sister chromatid segregation [IMP]
- response to mitotic cell cycle spindle assembly checkpoint signaling [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PLO1
Gene Ontology Biological Process
- mitotic actomyosin contractile ring assembly [IMP]
- mitotic cytokinesis, site selection [IMP]
- positive regulation of barrier septum assembly [IMP]
- positive regulation of protein export from nucleus [IMP]
- positive regulation of septation initiation signaling [IMP]
- regulation of mitotic cytokinesis [IMP]
- regulation of protein localization to mitotic spindle pole body [IMP]
- septation initiation signaling [IMP]
- spindle assembly involved in mitosis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Synthetic Growth Defect
A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell.
Publication
Regulation of cell cycle-specific gene expression in fission yeast by the Cdc14p-like phosphatase Clp1p.
Regulated gene expression makes an important contribution to cell cycle control mechanisms. In fission yeast, a group of genes is coordinately expressed during a late stage of the cell cycle (M phase and cytokinesis) that is controlled by common cis-acting promoter motifs named pombe cell cycle boxes (PCBs), which are bound by a trans-acting transcription factor complex, PCB binding factor ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: cell size (APO:0000052)
- phenotype: cell shape (APO:0000051)
- phenotype: vegetative growth (APO:0000106)
Additional Notes
- clp1 plo1-ts35 double mutant
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CLP1 PLO1 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 247822 | |
| PLO1 CLP1 | Synthetic Rescue Synthetic Rescue A genetic interaction is inferred when mutations or deletions of one gene rescues the lethality or growth defect of a strain mutated or deleted for another gene. | Low | - | BioGRID | 479742 |
Curated By
- BioGRID