CDC24
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
LRG1
Gene Ontology Biological Process
- cytogamy [IGI, IMP]
- negative regulation of Rho protein signal transduction [IGI, IMP]
- negative regulation of protein kinase C signaling [IGI, IMP]
- positive regulation of Rho GTPase activity [IDA]
- regulation of cell wall (1->3)-beta-D-glucan biosynthetic process [IGI]
- regulation of fungal-type cell wall organization [IGI, IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Synthetic Rescue
A genetic interaction is inferred when mutations or deletions of one gene rescues the lethality or growth defect of a strain mutated or deleted for another gene.
Publication
Mechanisms for concentrating Rho1 during cytokinesis.
The small GTP-binding protein, Rho1/RhoA plays a central role in cytokinetic actomyosin ring (CAR) assembly and cytokinesis. Concentration of Rho proteins at the division site is a general feature of cytokinesis, yet the mechanisms for recruiting Rho to the division site for cytokinesis remain poorly understood. We find that budding yeast utilizes two mechanisms to concentrate Rho1 at the division ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: viability (APO:0000111)
Additional Notes
- deletion of Lrg1 rescues the lethality of a Cdc24/Rom1/Rom2 triple mutant
- genetic complex
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CDC24 LRG1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.1323 | BioGRID | 354545 |
Curated By
- BioGRID