HDBP-2, HDBP2, HDRF-2, PBF, PRF-1, PRF1, Si-1-8-14
zinc finger protein 395
GO Process (1)
GO Function (2)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Homo sapiens


GON-10, HD1, RPD3, RPD3L1, RP4-811H24.2
histone deacetylase 1
GO Process (33)
GO Function (18)
GO Component (10)
Homo sapiens

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.


Papillomavirus binding factor binds to SAP30 and represses transcription via recruitment of the HDAC1 co-repressor complex.

Sichtig N, Koerfer N, Steger G

Papillomavirus binding factor, PBF, identical to the Huntington's disease binding protein 2, HDBP2, is a nuclear-cytoplasmic shuttling factor with the ability to inhibit cell growth. It has been identified by its ability to bind to GC-rich sequence elements within upstream promoter regions of certain human papillomavirus (HPV) types and of the Huntingtin protein, respectively. Here, we show that PBF acts ... [more]

Arch. Biochem. Biophys. Nov. 01, 2007; 467(1);67-75 [Pubmed: 17897615]


  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.


Curated By

  • BioGRID