BAIT
SKY1
serine/threonine protein kinase SKY1, L000003941, YMR216C
SR protein kinase (SRPK); involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1
GO Process (7)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Saccharomyces cerevisiae (S288c)
PREY
DBP2
DEAD-box ATP-dependent RNA helicase DBP2, L000000493, YNL112W
ATP-dependent RNA helicase of the DEAD-box protein family; has a strong preference for dsRNA; interacts with YRA1; required for the assembly of Yra1p, Nab2p and Mex67p onto mRNA and formation of nuclear mRNP; involved in mRNA decay and rRNA processing; may be involved in suppression of transcription from cryptic initiation sites
GO Process (4)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Saccharomyces cerevisiae (S288c)
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes.
Protein kinases are key regulators of cellular processes. In spite of considerable effort, a full understanding of the pathways they participate in remains elusive. We globally investigated the proteins that interact with the majority of yeast protein kinases using protein microarrays. Eighty-five kinases were purified and used to probe yeast proteome microarrays. One-thousand-twenty-three interactions were identified, and the vast majority ... [more]
Genes Dev. Apr. 01, 2011; 25(7);767-78 [Pubmed: 21460040]
Throughput
- High Throughput
Additional Notes
- High Throughput: Proteome microarrays were used to identify proteins that interact with protein kinases.
Curated By
- BioGRID