ARID1A
Gene Ontology Biological Process
- ATP-dependent chromatin remodeling [IDA]
- androgen receptor signaling pathway [ISO]
- cardiac chamber development [IMP]
- cardiac muscle cell differentiation [IMP]
- chromatin organization [IPI]
- chromatin remodeling [ISO]
- forebrain development [IMP]
- glucocorticoid receptor signaling pathway [ISO]
- intracellular estrogen receptor signaling pathway [ISO]
- maintenance of chromatin silencing [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- neural tube closure [IMP]
- nucleosome disassembly [ISO]
- optic cup formation involved in camera-type eye development [IMP]
- placenta blood vessel development [IMP]
- positive regulation of transcription, DNA-templated [ISO]
- toxin transport [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
E2F4
Gene Ontology Biological Process
- blood circulation [IMP]
- cell volume homeostasis [IMP]
- cilium assembly [IMP]
- epithelial cell development [IMP]
- organ morphogenesis [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- regulation of cell cycle [TAS]
- regulation of cell proliferation [IDA]
- regulation of cell size [IMP]
- regulation of transcription involved in G1/S transition of mitotic cell cycle [IDA, IGI]
- regulation of transcription, DNA-templated [TAS]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- protein domain specific binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO, TAS]
- transcription factor binding [ISO]
- DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- protein domain specific binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO, TAS]
- transcription factor binding [ISO]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control.
The mammalian SWI/SNF chromatin remodeling complex is becoming increasingly recognized for its role in tumor suppression, based on its ability to regulate accessibility of proliferation-associated genes to transcription factors. However, understanding the biological role of the complex is complicated because the same complex seemingly plays both positive and negative roles in gene expression. Work described here reveals that a choice ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| E2F4 ARID1A | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID