BAIT
CENPE
CENP-E, KIF10, MCPH13, PPP1R61
centromere protein E, 312kDa
GO Process (12)
GO Function (4)
GO Component (14)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- attachment of mitotic spindle microtubules to kinetochore [IMP]
- blood coagulation [TAS]
- kinetochore assembly [NAS]
- metabolic process [IMP]
- microtubule-based movement [IBA, TAS]
- mitotic cell cycle [IBA, TAS]
- mitotic chromosome movement towards spindle pole [TAS]
- mitotic metaphase plate congression [IMP]
- positive regulation of protein kinase activity [IMP]
- regulation of mitotic metaphase/anaphase transition [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- chromosome [IDA]
- chromosome, centromeric region [IDA]
- condensed chromosome outer kinetochore [TAS]
- condensed chromosome, centromeric region [IDA]
- cytoplasm [IDA]
- cytosol [TAS]
- kinesin complex [IBA]
- kinetochore [IDA]
- membrane [IDA]
- microtubule [IDA]
- microtubule cytoskeleton [IDA]
- midbody [IDA]
- mitotic spindle midzone [IDA]
- nucleus [IMP]
Homo sapiens
PREY
SEPT7
CDC10, CDC3, NBLA02942, SEPT7A
septin 7
GO Process (4)
GO Function (3)
GO Component (10)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Identification of FANCA as a protein interacting with centromere-associated protein E.
This study sought to isolate and identify proteins that interact with centromere-associated protein E (CENPE), provide new clues for exploring the function of CENP-E in cell cycle control and the pathogenesis of tumor. Yeast two-hybrid screen and regular molecular biologic techniques were undertaken to screen human HeLa cDNA library with the kinetochore binding domain of CENP-E. The bait from the ... [more]
Acta Biochim. Biophys. Sin. (Shanghai) Oct. 01, 2009; 41(10);816-21 [Pubmed: 19779646]
Throughput
- Low Throughput
Curated By
- BioGRID