SNF1
Gene Ontology Biological Process
- cell adhesion [IMP]
- cellular response to nitrogen starvation [IDA]
- fungal-type cell wall assembly [IMP]
- invasive growth in response to glucose limitation [IMP]
- negative regulation of translation [IGI, IMP]
- positive regulation of filamentous growth of a population of unicellular organisms in response to starvation [IMP]
- positive regulation of gluconeogenesis [IMP]
- protein phosphorylation [IDA]
- pseudohyphal growth [IMP]
- regulation of carbohydrate metabolic process [IGI, IPI]
- replicative cell aging [IGI, IMP]
- single-species surface biofilm formation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
MSN2
Gene Ontology Biological Process
- age-dependent response to oxidative stress involved in chronological cell aging [IGI]
- cellular response to blue light [IDA]
- cellular response to methylmercury [IGI, IMP]
- chromatin remodeling [IGI]
- positive regulation of transcription from RNA polymerase II promoter [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [IGI, IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to cold [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to ethanol [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to freezing [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to heat stress [IGI, IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide [IGI, IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to increased salt [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [IGI]
- regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction [IGI]
- replicative cell aging [IGI]
Gene Ontology Molecular Function
Synthetic Growth Defect
A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell.
Publication
The role of the protein kinase A pathway in the response to alkaline pH stress in yeast.
Exposure of Saccharomyces cerevisiae to alkaline pH provokes a stress condition that generates a compensatory reaction. In the present study we examined a possible role for the PKA (protein kinase A) pathway in this response. Phenotypic analysis revealed that mutations that activate the PKA pathway (ira1 ira2, bcy1) tend to cause sensitivity to alkaline pH, whereas its deactivation enhances tolerance ... [more]
Throughput
- Low Throughput
Ontology Terms
- vegetative growth (APO:0000106)
- alkaline ph resistance (APO:0000202)
Additional Notes
- deletion of msn2 and msn4 increases the sensitivity of a snf1 mutant to alkaline pH
- genetic complex
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SNF1 MSN2 | Biochemical Activity Biochemical Activity An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation. | Low | - | BioGRID | 195427 | |
| SNF1 MSN2 | Dosage Rescue Dosage Rescue A genetic interaction is inferred when over expression or increased dosage of one gene rescues the lethality or growth defect of a strain that is mutated or deleted for another gene. | Low | - | BioGRID | 154841 | |
| SNF1 MSN2 | Dosage Rescue Dosage Rescue A genetic interaction is inferred when over expression or increased dosage of one gene rescues the lethality or growth defect of a strain that is mutated or deleted for another gene. | Low | - | BioGRID | 2339800 | |
| MSN2 SNF1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -4.1054 | BioGRID | 542332 | |
| SNF1 MSN2 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 2339815 |
Curated By
- BioGRID