BAIT
CUL3
AI467304, AW146203, mKIAA0617
cullin 3
GO Process (26)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- COPII vesicle coating [ISO]
- ER to Golgi vesicle-mediated transport [ISO]
- Wnt signaling pathway [IDA]
- cell migration [ISO]
- cell morphogenesis [IMP]
- embryonic cleavage [IMP]
- fibroblast apoptotic process [IMP]
- gastrulation [IMP]
- in utero embryonic development [IMP]
- integrin-mediated signaling pathway [IMP]
- liver morphogenesis [IMP]
- mitotic cell cycle [IMP]
- mitotic metaphase plate congression [ISO]
- negative regulation of Rho protein signal transduction [ISO]
- negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of cytokinesis [ISO]
- positive regulation of mitotic metaphase/anaphase transition [ISO]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IGI, ISO]
- protein monoubiquitination [ISO]
- protein polyubiquitination [ISO]
- protein ubiquitination [ISO]
- regulation of transcription from RNA polymerase II promoter [IGI]
- stem cell division [IMP]
- stress fiber assembly [ISO]
- trophectodermal cellular morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
GOLGA2
GM130, RP11-395P17.5
golgin A2
GO Process (2)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of ... [more]
Science Apr. 30, 2010; 328(5978);593-9 [Pubmed: 20360068]
Throughput
- High Throughput
Curated By
- BioGRID