BAIT
YWHAE
AU019196, RP23-78H4.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
GO Process (8)
GO Function (12)
GO Component (6)
Gene Ontology Biological Process
- cerebral cortex development [IMP]
- hippocampus development [IMP]
- negative regulation of peptidyl-serine dephosphorylation [ISO]
- negative regulation of protein dephosphorylation [IDA]
- neuron migration [IGI, IMP]
- protein targeting [IDA]
- regulation of membrane repolarization [ISO]
- regulation of potassium ion transmembrane transporter activity [ISO]
Gene Ontology Molecular Function- MHC class II protein complex binding [ISO]
- enzyme binding [ISO]
- histone deacetylase binding [ISO]
- ion channel binding [ISO]
- phosphoprotein binding [ISO]
- phosphoserine binding [ISO]
- poly(A) RNA binding [ISO]
- potassium channel regulator activity [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein domain specific binding [IDA]
- protein heterodimerization activity [ISO]
- MHC class II protein complex binding [ISO]
- enzyme binding [ISO]
- histone deacetylase binding [ISO]
- ion channel binding [ISO]
- phosphoprotein binding [ISO]
- phosphoserine binding [ISO]
- poly(A) RNA binding [ISO]
- potassium channel regulator activity [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein domain specific binding [IDA]
- protein heterodimerization activity [ISO]
Gene Ontology Cellular Component
Mus musculus
PREY
AHI1
1700015F03Rik, Ahi-1, D10Bwg0629e
Abelson helper integration site 1
GO Process (24)
GO Function (2)
GO Component (10)
Gene Ontology Biological Process
- cellular protein localization [IGI]
- central nervous system development [IGI]
- cilium assembly [IMP]
- cilium morphogenesis [IMP]
- cloaca development [IGI]
- heart looping [IGI]
- hindbrain development [IGI]
- morphogenesis of a polarized epithelium [IMP]
- negative regulation of apoptotic process [IMP]
- otic vesicle development [IGI]
- photoreceptor cell outer segment organization [IGI, IMP]
- positive regulation of gene expression [IMP]
- positive regulation of polarized epithelial cell differentiation [IMP]
- positive regulation of receptor internalization [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- pronephric nephron tubule morphogenesis [IGI]
- protein localization to organelle [IMP]
- regulation of behavior [IMP]
- retina development in camera-type eye [IMP]
- retina layer formation [IGI]
- specification of axis polarity [IGI]
- transmembrane receptor protein tyrosine kinase signaling pathway [IMP]
- vesicle targeting [IMP]
- vesicle-mediated transport [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification of 14-3-3epsilon substrates from embryonic murine brain.
Mice deficient in 14-3-3epsilon exhibit abnormal neuronal migration and die perinatally. We report here the first large-scale analysis of 14-3-3 interacting partners from primary animal tissue, identifying from embryonic murine brain 163 14-3-3epsilon interacting proteins and 85 phosphorylation sites on these proteins. Phosphorylation of the deubiquitinating enzyme USP8 at serine 680 was found essential for its interaction with 14-3-3epsilon and ... [more]
J. Proteome Res. Sep. 01, 2006; 5(9);2372-9 [Pubmed: 16944949]
Throughput
- High Throughput
Curated By
- BioGRID