BAIT
APOC1
Apo-CI, ApoC-I
apolipoprotein C-I
GO Process (19)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
- cholesterol efflux [IDA]
- chylomicron remnant clearance [IDA]
- high-density lipoprotein particle remodeling [TAS]
- lipid metabolic process [TAS]
- negative regulation of cholesterol transport [IDA]
- negative regulation of fatty acid biosynthetic process [IDA]
- negative regulation of lipid catabolic process [IDA]
- negative regulation of lipid metabolic process [IDA]
- negative regulation of lipoprotein lipase activity [IDA]
- negative regulation of phosphatidylcholine catabolic process [IDA]
- negative regulation of receptor-mediated endocytosis [IDA]
- negative regulation of very-low-density lipoprotein particle clearance [IDA]
- phospholipid efflux [IDA]
- plasma lipoprotein particle remodeling [IDA]
- positive regulation of catalytic activity [TAS]
- positive regulation of cholesterol esterification [TAS]
- regulation of cholesterol transport [IC]
- very-low-density lipoprotein particle assembly [TAS]
- very-low-density lipoprotein particle clearance [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID