BAIT
COMMD8
MDS022
COMM domain containing 8
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
PREY
AKR1C1
2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB, RP11-69D4.1
aldo-keto reductase family 1, member C1
GO Process (17)
GO Function (9)
GO Component (2)
Gene Ontology Biological Process
- bile acid and bile salt transport [TAS]
- bile acid metabolic process [IDA]
- cellular response to jasmonic acid stimulus [IDA]
- cholesterol homeostasis [TAS]
- daunorubicin metabolic process [IMP]
- digestion [IDA]
- doxorubicin metabolic process [IMP]
- epithelial cell differentiation [IDA]
- intestinal cholesterol absorption [TAS]
- oxidation-reduction process [IDA]
- phototransduction, visible light [TAS]
- progesterone metabolic process [IDA]
- protein homooligomerization [IDA]
- response to organophosphorus [IEP]
- retinal metabolic process [IDA]
- retinoid metabolic process [TAS]
- xenobiotic metabolic process [NAS]
Gene Ontology Molecular Function- alditol:NADP+ 1-oxidoreductase activity [IDA]
- aldo-keto reductase (NADP) activity [TAS]
- androsterone dehydrogenase (B-specific) activity [IDA]
- bile acid binding [IDA]
- carboxylic acid binding [IDA]
- ketosteroid monooxygenase activity [IDA]
- oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [IDA]
- phenanthrene 9,10-monooxygenase activity [IDA]
- trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [IDA]
- alditol:NADP+ 1-oxidoreductase activity [IDA]
- aldo-keto reductase (NADP) activity [TAS]
- androsterone dehydrogenase (B-specific) activity [IDA]
- bile acid binding [IDA]
- carboxylic acid binding [IDA]
- ketosteroid monooxygenase activity [IDA]
- oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [IDA]
- phenanthrene 9,10-monooxygenase activity [IDA]
- trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [IDA]
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A directed protein interaction network for investigating intracellular signal transduction.
Cellular signal transduction is a complex process involving protein-protein interactions (PPIs) that transmit information. For example, signals from the plasma membrane may be transduced to transcription factors to regulate gene expression. To obtain a global view of cellular signaling and to predict potential signal modulators, we searched for protein interaction partners of more than 450 signaling-related proteins by means of ... [more]
Sci Signal Sep. 06, 2011; 4(189);rs8 [Pubmed: 21900206]
Throughput
- High Throughput
Curated By
- BioGRID