Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

CBX3 regulates efficient RNA processing genome-wide.

Smallwood A, Hon GC, Jin F, Henry RE, Espinosa JE, Ren B

CBX5, CBX1, and CBX3 (HP1α, β, and γ respectively) play an evolutionarily conserved role in the formation and maintenance of heterochromatin. In addition, CBX5, CBX1, and CBX3 may also participate in transcriptional regulation of genes. Recently, CBX3 binding to the bodies of a subset of genes has been observed in human and murine cells. However, the generality of this phenomenon ... [more]

Unknown Jun. 08, 2012; 0(0); [Pubmed: 22684280]

Throughput

  • Low Throughput

Additional Notes

  • figure S1E.

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
CBX3 H3F3A
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High-BioGRID
-
H3F3A CBX3
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Low-BioGRID
-

Curated By

  • BioGRID