BAIT
IMMT
HMP, MINOS2, P87, P87/89, P89, PIG52, PIG4
inner membrane protein, mitochondrial
GO Process (0)
GO Function (2)
GO Component (3)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PIAS4
PIASY, Piasg, ZMIZ6
protein inhibitor of activated STAT, 4
GO Process (4)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.
Analysis of protein-protein interactions (PPIs) is a valuable approach for characterizing proteins of unknown function. Here, we have developed a strategy combining library and matrix yeast two-hybrid screens to generate a highly connected PPI network for Huntington's disease (HD). The network contains 186 PPIs among 35 bait and 51 prey proteins. It revealed 165 new potential interactions, 32 of which ... [more]
Mol. Cell Sep. 24, 2004; 15(6);853-65 [Pubmed: 15383276]
Throughput
- High Throughput
Curated By
- BioGRID