BAIT
ALYREF
ALY, ALY/REF, BEF, REF, THOC4
Aly/REF export factor
GO Process (12)
GO Function (2)
GO Component (9)
Gene Ontology Biological Process
- RNA splicing [TAS]
- gene expression [TAS]
- mRNA 3'-end processing [TAS]
- mRNA export from nucleus [IMP, TAS]
- mRNA splicing, via spliceosome [IC, TAS]
- osteoblast differentiation [IDA]
- positive regulation of DNA-templated transcription, elongation [IMP]
- regulation of DNA recombination [IMP]
- replication fork processing [IMP]
- termination of RNA polymerase II transcription [TAS]
- transcription from RNA polymerase II promoter [TAS]
- viral mRNA export from host cell nucleus [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NR5A1
AD4BP, ELP, FTZ1, FTZF1, POF7, SF-1, SF1, SPGF8, SRXY3, RP11-101K10.1
nuclear receptor subfamily 5, group A, member 1
GO Process (8)
GO Function (7)
GO Component (2)
Gene Ontology Biological Process
- cell-cell signaling [TAS]
- gene expression [TAS]
- intracellular receptor signaling pathway [TAS]
- positive regulation of male gonad development [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- primary sex determination [TAS]
- regulation of steroid biosynthetic process [TAS]
- transcription initiation from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- enzyme binding [IPI]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [TAS]
- phospholipid binding [IDA]
- protein binding [IPI]
- transcription coactivator activity [TAS]
- DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- enzyme binding [IPI]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [TAS]
- phospholipid binding [IDA]
- protein binding [IPI]
- transcription coactivator activity [TAS]
Gene Ontology Cellular Component
- nucleoplasm [TAS]
- nucleus [IDA]
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Human mRNA export machinery recruited to the 5' end of mRNA.
Pre-mRNAs undergo splicing to remove introns, and the spliced mRNA is exported to the cytoplasm for translation. Here we investigated the mechanism for recruitment of the conserved mRNA export machinery (TREX complex) to mRNA. We show that the human TREX complex is recruited to a region near the 5' end of mRNA, with the TREX component Aly bound closest to ... [more]
Cell Dec. 29, 2006; 127(7);1389-400 [Pubmed: 17190602]
Throughput
- Low Throughput
Curated By
- BioGRID