BAIT
NUP214
CAIN, CAN, D9S46E, N214, p250, RP11-544A12.7
nucleoporin 214kDa
GO Process (14)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- carbohydrate metabolic process [TAS]
- cytokine-mediated signaling pathway [TAS]
- gene expression [TAS]
- glucose transport [TAS]
- hexose transport [TAS]
- mRNA metabolic process [TAS]
- mitotic cell cycle [TAS]
- mitotic nuclear envelope disassembly [TAS]
- protein export from nucleus [IMP]
- regulation of glucose transport [TAS]
- small molecule metabolic process [TAS]
- transmembrane transport [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NUPL2
CG1, NLP-1, NLP_1, hCG1
nucleoporin like 2
GO Process (11)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- carbohydrate metabolic process [TAS]
- cytokine-mediated signaling pathway [TAS]
- glucose transport [TAS]
- hexose transport [TAS]
- mitotic cell cycle [TAS]
- mitotic nuclear envelope disassembly [TAS]
- protein export from nucleus [TAS]
- regulation of glucose transport [TAS]
- small molecule metabolic process [TAS]
- transmembrane transport [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human.
Human TAP is an orthologue of the yeast mRNA export factor Mex67p. In mammalian cells, TAP has a preferential intranuclear localization, but can also be detected at the nuclear pores and shuttles between the nucleus and the cytoplasm. TAP directly associates with mRNA in vivo, as it can be UV-crosslinked to poly(A)+ RNA in HeLa cells. Both the FG-repeat domain ... [more]
EMBO J. May. 04, 1999; 18(9);2593-609 [Pubmed: 10228171]
Throughput
- Low Throughput
Curated By
- BioGRID