BAIT

HSPA4

APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY
heat shock 70kDa protein 4
GO Process (3)
GO Function (1)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

TCP1

CCT-alpha, CCT1, CCTa, D6S230E, TCP-1-alpha
t-complex 1
Homo sapiens

Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

Publication

A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death.

Imai Y, Soda M, Murakami T, Shoji M, Abe K, Takahashi R

Parkin, a RING-type ubiquitin ligase, is the product of the gene responsible for autosomal recessive juvenile parkinsonism. A reverse strand gene located upstream of the parkin gene in the human genome has been identified. The gene product, termed Glup/PACRG, forms a large molecular chaperone complex containing heat shock proteins 70 and 90 and chaperonin components. Glup suppressed cell death induced ... [more]

J. Biol. Chem. Dec. 19, 2003; 278(51);51901-10 [Pubmed: 14532270]

Throughput

  • Low Throughput

Ontology Terms

  • cell line: hek-293t cell (BTO:0002181)

Additional Notes

  • figure 1.

Curated By

  • BioGRID