BAIT

MED21

0610007L03Rik, AI449604, D19234, D6Ertd782e, Srb7, Surb7, RP23-158O11.4
mediator complex subunit 21
Mus musculus
PREY

AAGAB

2310007F21Rik, p34
alpha- and gamma-adaptin binding protein
GO Process (0)
GO Function (0)
GO Component (2)

Gene Ontology Cellular Component

Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways.

Jiang YW, Veschambre P, Erdjument-Bromage H, Tempst P, Conaway JW, Conaway RC, Kornberg RD

A multiprotein complex isolated from murine cells is identified as a counterpart of the yeast Mediator of transcriptional regulation on the basis of the following: homologs of two subunits of yeast Mediator, Srb7 and Med7, copurify with the complex; peptide sequencing reveals, in addition, homologs of the yeast Mediator subunits Rgr1 and Med6; as with yeast Mediator, the mouse complex ... [more]

Proc. Natl. Acad. Sci. U.S.A. Jul. 21, 1998; 95(15);8538-43 [Pubmed: 9671713]

Throughput

  • Low Throughput

Curated By

  • BioGRID