BAIT
HCFC1
CFF, HCF, HCF-1, HCF1, HFC1, MRX3, PPP1R89, VCAF
host cell factor C1
GO Process (12)
GO Function (8)
GO Component (12)
Gene Ontology Biological Process
- chromatin organization [TAS]
- histone H4-K16 acetylation [IDA]
- histone H4-K5 acetylation [IDA]
- histone H4-K8 acetylation [IDA]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of cell cycle [TAS]
- positive regulation of gene expression [IDA]
- protein stabilization [IDA]
- regulation of protein complex assembly [IDA]
- regulation of transcription, DNA-templated [IDA]
- release from viral latency [NAS]
- transcription from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function- chromatin binding [IDA]
- histone acetyltransferase activity (H4-K16 specific) [IDA]
- histone acetyltransferase activity (H4-K5 specific) [IDA]
- histone acetyltransferase activity (H4-K8 specific) [IDA]
- identical protein binding [IPI]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
- transcription coactivator activity [IMP]
- chromatin binding [IDA]
- histone acetyltransferase activity (H4-K16 specific) [IDA]
- histone acetyltransferase activity (H4-K5 specific) [IDA]
- histone acetyltransferase activity (H4-K8 specific) [IDA]
- identical protein binding [IPI]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
- transcription coactivator activity [IMP]
Gene Ontology Cellular Component
Homo sapiens
PREY
PPP1CB
HEL-S-80p, PP-1B, PP1B, PP1beta, PPP1CD
protein phosphatase 1, catalytic subunit, beta isozyme
GO Process (11)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [TAS]
- circadian regulation of gene expression [ISS]
- entrainment of circadian clock by photoperiod [ISS]
- mitotic cell cycle [TAS]
- negative regulation of transforming growth factor beta receptor signaling pathway [TAS]
- protein dephosphorylation [ISS]
- regulation of cell adhesion [IDA]
- regulation of circadian rhythm [IMP]
- small molecule metabolic process [TAS]
- transforming growth factor beta receptor signaling pathway [TAS]
- triglyceride catabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A census of human soluble protein complexes.
Cellular processes often depend on stable physical associations between proteins. Despite recent progress, knowledge of the composition of human protein complexes remains limited. To close this gap, we applied an integrative global proteomic profiling approach, based on chromatographic separation of cultured human cell extracts into more than one thousand biochemical fractions that were subsequently analyzed by quantitative tandem mass spectrometry, ... [more]
Cell Aug. 31, 2012; 150(5);1068-81 [Pubmed: 22939629]
Quantitative Score
- 0.825 [Denoised score]
Throughput
- High Throughput
Additional Notes
- Denoised score >= 0.75
Curated By
- BioGRID