BAIT
TUFM
COXPD4, EF-TuMT, EFTU, P43
Tu translation elongation factor, mitochondrial
GO Process (1)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ENG
END, HHT1, ORW1, RP11-228B15.2
endoglin
GO Process (35)
GO Function (11)
GO Component (7)
Gene Ontology Biological Process
- BMP signaling pathway [TAS]
- artery morphogenesis [ISS]
- cell chemotaxis [IMP]
- cell migration [IMP]
- cell motility [IMP]
- central nervous system vasculogenesis [IMP]
- chronological cell aging [IEP]
- detection of hypoxia [IDA]
- extracellular matrix disassembly [IMP]
- heart looping [ISS]
- intracellular signal transduction [IDA]
- negative regulation of cell migration [IDA]
- negative regulation of endothelial cell proliferation [IMP]
- negative regulation of nitric-oxide synthase activity [IMP]
- negative regulation of pathway-restricted SMAD protein phosphorylation [IMP]
- negative regulation of protein autophosphorylation [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transforming growth factor beta receptor signaling pathway [TAS]
- patterning of blood vessels [ISS]
- positive regulation of BMP signaling pathway [IDA]
- positive regulation of pathway-restricted SMAD protein phosphorylation [IDA, IMP]
- positive regulation of protein phosphorylation [IDA]
- positive regulation of systemic arterial blood pressure [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of cell adhesion [TAS]
- regulation of cell proliferation [TAS]
- regulation of phosphorylation [TAS]
- regulation of transcription, DNA-templated [IMP]
- regulation of transforming growth factor beta receptor signaling pathway [IDA]
- response to hypoxia [IDA]
- smooth muscle tissue development [ISS]
- transforming growth factor beta receptor signaling pathway [IDA]
- vasculogenesis [IMP]
- venous blood vessel morphogenesis [ISS]
- wound healing [IMP]
Gene Ontology Molecular Function- activin binding [TAS]
- galactose binding [IDA]
- glycosaminoglycan binding [IDA, ISS]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- transforming growth factor beta binding [IPI]
- transforming growth factor beta receptor, cytoplasmic mediator activity [IDA]
- transforming growth factor beta-activated receptor activity [IDA]
- transmembrane signaling receptor activity [NAS]
- type I transforming growth factor beta receptor binding [IPI, ISS]
- type II transforming growth factor beta receptor binding [IPI, ISS]
- activin binding [TAS]
- galactose binding [IDA]
- glycosaminoglycan binding [IDA, ISS]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- transforming growth factor beta binding [IPI]
- transforming growth factor beta receptor, cytoplasmic mediator activity [IDA]
- transforming growth factor beta-activated receptor activity [IDA]
- transmembrane signaling receptor activity [NAS]
- type I transforming growth factor beta receptor binding [IPI, ISS]
- type II transforming growth factor beta receptor binding [IPI, ISS]
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A census of human soluble protein complexes.
Cellular processes often depend on stable physical associations between proteins. Despite recent progress, knowledge of the composition of human protein complexes remains limited. To close this gap, we applied an integrative global proteomic profiling approach, based on chromatographic separation of cultured human cell extracts into more than one thousand biochemical fractions that were subsequently analyzed by quantitative tandem mass spectrometry, ... [more]
Cell Aug. 31, 2012; 150(5);1068-81 [Pubmed: 22939629]
Quantitative Score
- 0.774 [Denoised score]
Throughput
- High Throughput
Additional Notes
- Denoised score >= 0.75
Curated By
- BioGRID