BAIT

ECT2

ARHGEF31
epithelial cell transforming 2
GO Process (22)
GO Function (5)
GO Component (11)
Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Charting the landscape of tandem BRCT domain-mediated protein interactions.

Woods NT, Mesquita RD, Sweet M, Carvalho MA, Li X, Liu Y, Nguyen H, Thomas CE, Iversen ES, Marsillac S, Karchin R, Koomen J, Monteiro AN

Eukaryotic cells have evolved an intricate system to resolve DNA damage to prevent its transmission to daughter cells. This system, collectively known as the DNA damage response (DDR) network, includes many proteins that detect DNA damage, promote repair, and coordinate progression through the cell cycle. Because defects in this network can lead to cancer, this network constitutes a barrier against ... [more]

Sci Signal Sep. 20, 2012; 5(242);rs6 [Pubmed: 22990118]

Throughput

  • High Throughput

Curated By

  • BioGRID