ECT2
Gene Ontology Biological Process
- activation of Rac GTPase activity [IMP]
- activation of Rho GTPase activity [IDA]
- activation of protein kinase activity [IDA]
- apoptotic signaling pathway [TAS]
- cellular response to calcium ion [IDA]
- cellular response to hydrogen peroxide [IDA]
- cellular response to ionizing radiation [IDA]
- cytokinesis [IMP]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of Cdc42 GTPase activity [IDA]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- positive regulation of Rho GTPase activity [IDA, IMP]
- positive regulation of apoptotic process [IDA, TAS]
- positive regulation of cytokinesis [IDA, IMP]
- positive regulation of neuron differentiation [ISS]
- positive regulation of protein import into nucleus [ISS]
- protein homooligomerization [IDA]
- regulation of attachment of spindle microtubules to kinetochore [IMP]
- regulation of protein kinase activity [IDA]
- regulation of small GTPase mediated signal transduction [TAS]
- small GTPase mediated signal transduction [TAS]
- tight junction assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CTBP1
Gene Ontology Biological Process
- chromatin organization involved in regulation of transcription [IMP]
- negative regulation of cell proliferation [TAS]
- negative regulation of histone H4 acetylation [IMP]
- negative regulation of histone acetylation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- negative regulation of transcription, DNA-templated [ISS]
- positive regulation of histone deacetylation [IMP]
- protein phosphorylation [TAS]
- regulation of cell cycle [IMP]
- viral genome replication [TAS]
- white fat cell differentiation [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Charting the landscape of tandem BRCT domain-mediated protein interactions.
Eukaryotic cells have evolved an intricate system to resolve DNA damage to prevent its transmission to daughter cells. This system, collectively known as the DNA damage response (DDR) network, includes many proteins that detect DNA damage, promote repair, and coordinate progression through the cell cycle. Because defects in this network can lead to cancer, this network constitutes a barrier against ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ECT2 CTBP1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9696 | BioGRID | 3294764 |
Curated By
- BioGRID