BAIT
LIG4
LIG4S
ligase IV, DNA, ATP-dependent
GO Process (27)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- DNA ligation [IDA]
- DNA ligation involved in DNA recombination [ISS]
- DNA ligation involved in DNA repair [IDA, ISS]
- DNA repair [TAS]
- T cell differentiation in thymus [ISS]
- T cell receptor V(D)J recombination [ISS]
- V(D)J recombination [IDA]
- cell proliferation [ISS]
- central nervous system development [ISS]
- chromosome organization [ISS]
- double-strand break repair [IDA, ISS, TAS]
- double-strand break repair via nonhomologous end joining [IDA, IMP, TAS]
- establishment of integrated proviral latency [TAS]
- in utero embryonic development [ISS]
- isotype switching [ISS]
- lagging strand elongation [IBA]
- negative regulation of neuron apoptotic process [ISS]
- neuron apoptotic process [ISS]
- nucleotide-excision repair, DNA gap filling [IDA]
- positive regulation of fibroblast proliferation [ISS]
- positive regulation of neurogenesis [ISS]
- pro-B cell differentiation [ISS]
- response to X-ray [IMP]
- response to gamma radiation [ISS]
- single strand break repair [IDA]
- somatic stem cell maintenance [ISS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NDUFB10
PDSW
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa
GO Process (4)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Charting the landscape of tandem BRCT domain-mediated protein interactions.
Eukaryotic cells have evolved an intricate system to resolve DNA damage to prevent its transmission to daughter cells. This system, collectively known as the DNA damage response (DDR) network, includes many proteins that detect DNA damage, promote repair, and coordinate progression through the cell cycle. Because defects in this network can lead to cancer, this network constitutes a barrier against ... [more]
Sci Signal Sep. 20, 2012; 5(242);rs6 [Pubmed: 22990118]
Throughput
- High Throughput
Curated By
- BioGRID