CATSPER1
Gene Ontology Biological Process
- calcium ion import [IBA]
- calcium ion transmembrane transport [IMP]
- calcium ion transport [IMP]
- fusion of sperm to egg plasma membrane [IMP]
- membrane depolarization during action potential [IBA]
- regulation of calcium ion transport [IMP]
- regulation of cilium beat frequency involved in ciliary motility [IMP]
- regulation of ion transmembrane transport [IMP]
- sperm motility [IMP]
- spermatogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CATSPERB
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
CatSperbeta, a novel transmembrane protein in the CatSper channel complex.
Four CatSper ion channel subunit genes (CatSpers 1-4) are required for sperm cell hyperactivation and male fertility. The four proteins assemble (presumably as a tetramer) to form a sperm-specific, alkalinization-activated Ca(2+)-selective channel. We set out to identify proteins associating with CatSper that might help explain its unique role in spermatozoa. Using a transgenic approach, a CatSper1 complex was purified from ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CATSPERB CATSPER1 | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 0.934 | BioGRID | 2678459 |
Curated By
- BioGRID