CPEB1
Gene Ontology Biological Process
Gene Ontology Molecular Function
APLP2
Gene Ontology Biological Process
- cellular copper ion homeostasis [IMP]
- cholesterol metabolic process [IGI]
- embryo development [IGI]
- extracellular matrix organization [IGI]
- forebrain development [IGI]
- locomotory behavior [IGI]
- mating behavior [IGI]
- midbrain development [IGI]
- neuromuscular process controlling balance [IGI]
- regulation of epidermal growth factor-activated receptor activity [IGI]
- regulation of protein binding [IGI]
- suckling behavior [IGI]
Gene Ontology Molecular Function
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation.
The cytoplasmic polyadenylation element (CPE) binding factor, CPEB, is a sequence-specific RNA binding protein that controls polyadenylation-induced translation in germ cells and at postsynaptic sites of neurons. A yeast two-hybrid screen with a mouse brain cDNA library identified the transmembrane amyloid precursor-like protein 1 (APLP1) as a CPEB-interacting factor. CPEB binds the small intracellular domain (ICD) of APLP1 and the ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID