BAIT
HSPA5
AL022860, AU019543, Bip, D2Wsu141e, D2Wsu17e, Grp78, Hsce70, SEZ-7, Sez7, baffled, mBiP, RP23-446N16.1
heat shock protein 5
GO Process (15)
GO Function (8)
GO Component (17)
Gene Ontology Biological Process
- ER overload response [IDA]
- activation of signaling protein activity involved in unfolded protein response [IMP]
- cellular response to glucose starvation [ISO]
- cellular response to interleukin-4 [IDA]
- cerebellar Purkinje cell layer development [IMP]
- cerebellum structural organization [IMP]
- maintenance of protein localization in endoplasmic reticulum [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of transforming growth factor beta receptor signaling pathway [IGI]
- positive regulation of cell migration [ISO]
- positive regulation of embryonic development [TAS]
- positive regulation of protein ubiquitination [IMP]
- proteolysis involved in cellular protein catabolic process [IDA]
- response to endoplasmic reticulum stress [ISO]
- toxin transport [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- COP9 signalosome [ISO]
- cell surface [IDA]
- endoplasmic reticulum [IDA, ISO]
- endoplasmic reticulum chaperone complex [ISO]
- endoplasmic reticulum lumen [IDA]
- endoplasmic reticulum membrane [IDA]
- endoplasmic reticulum-Golgi intermediate compartment [IDA, ISO]
- extracellular vesicular exosome [ISO]
- focal adhesion [ISO]
- integral component of endoplasmic reticulum membrane [ISO]
- membrane [ISO]
- midbody [ISO]
- mitochondrion [ISO]
- myelin sheath [IDA]
- nucleus [ISO]
- plasma membrane [IDA]
- smooth endoplasmic reticulum [ISO]
Mus musculus
PREY
FKBP7
23kDa, FKBP-7, FKBP23, RP23-468L22.3
FK506 binding protein 7
GO Process (2)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
The mouse FKBP23 binds to BiP in ER and the binding of C-terminal domain is interrelated with Ca2+ concentration.
FK506 binding protein 23 from mouse (mFKBP23) is a peptidyl-prolyl cis-trans isomerase (PPIase) from the endoplasmic reticulum (ER), which consists of an N-terminal PPIase domain and a C-terminal domain with Ca(2+) binding sites. The assay of adsorption from ER extract with glutathione S-transferase-mFKBP23 attached to glutathione-Sepharose 4B shows that mFKBP23 binds to mouse immunoglobulin binding protein (mBiP). The same assay ... [more]
FEBS Lett. Feb. 13, 2004; 559(1);57-60 [Pubmed: 14960307]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| FKBP7 HSPA5 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID