BAIT
SNTA1
LQT12, SNT1, TACIP1, dJ1187J4.5
syntrophin, alpha 1
GO Process (6)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
AGTR2
AT2, ATGR2, MRX88
angiotensin II receptor, type 2
GO Process (20)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IC]
- G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [ISS]
- angiotensin-activated signaling pathway [IPI, TAS]
- blood vessel remodeling [TAS]
- brain development [NAS]
- cell surface receptor signaling pathway [IDA]
- extracellular negative regulation of signal transduction [TAS]
- intracellular signal transduction [ISS]
- negative regulation of blood vessel endothelial cell migration [NAS]
- negative regulation of cell growth [TAS]
- negative regulation of heart rate [ISS]
- negative regulation of neurotrophin TRK receptor signaling pathway [IMP]
- nitric oxide mediated signal transduction [IC, TAS]
- positive regulation of extrinsic apoptotic signaling pathway [IMP]
- positive regulation of nitric oxide biosynthetic process [IC]
- positive regulation of nitric-oxide synthase activity [ISS]
- positive regulation of phosphoprotein phosphatase activity [IDA]
- positive regulation of vasodilation [IDA]
- regulation of blood pressure [TAS]
- regulation of systemic arterial blood pressure by circulatory renin-angiotensin [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.
SPOT synthesis permits parallel synthesis and screening of thousands of cellulose membrane-bound peptides to study protein-protein interactions in a proteomic context. Recognition of C-terminal residues is one of the most common binding features of PDZ domains. Unfortunately, most solid support-bound peptide libraries lack a free C terminus due to C-terminal fixation on the solid support. To overcome this restriction, we ... [more]
Chem. Biol. Apr. 01, 2004; 11(4);449-59 [Pubmed: 15123239]
Throughput
- Low Throughput
Curated By
- BioGRID