BAIT
CAPN1
CANP, CANP1, CANPL1, muCANP, muCL, PIG30
calpain 1, (mu/I) large subunit
GO Process (4)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PTGDS
L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2, RP11-229P13.6
prostaglandin D2 synthase 21kDa (brain)
GO Process (6)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Screening the proteins that interact with calpain in a human heart cDNA library using a yeast two-hybrid system.
Calpain, a cytosolic cysteine protease, requires calcium ions for activity. It has been reported that calpain is involved in the degradation of myofibrillar and neurofilament proteins, and the activation of phosphorylase b kinase and protein kinase C. More recently, calpain was shown to participate in apoptosis. In order to understand the calpain-related signal transduction pathway and its changes during hypertrophy, ... [more]
Hypertens. Res. Jul. 01, 2002; 25(4);647-52 [Pubmed: 12358155]
Throughput
- Low Throughput
Curated By
- BioGRID