BAIT
USP19
ZMYND9
ubiquitin specific peptidase 19
GO Process (8)
GO Function (4)
GO Component (1)
Gene Ontology Biological Process
- ER-associated ubiquitin-dependent protein catabolic process [IDA]
- negative regulation of skeletal muscle tissue development [ISS]
- positive regulation of cell cycle process [ISS]
- protein deubiquitination [IBA, ISS]
- regulation of cellular response to hypoxia [IMP]
- regulation of proteasomal protein catabolic process [IBA]
- regulation of protein stability [ISS]
- response to endoplasmic reticulum stress [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CKAP5
CHTOG, MSPS, TOG, TOGp, ch-TOG
cytoskeleton associated protein 5
GO Process (6)
GO Function (1)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
An N-terminal SIAH-interacting motif regulates the stability of the ubiquitin specific protease (USP)-19.
The Ubiquitin Specific Protease-19 (USP19) regulates cell cycle progression and is involved in the cellular response to different types of stress, including the unfolded protein response (UPR), hypoxia and muscle atrophy. Using the unique N-terminal domain as bait in a yeast-two hybrid screen we have identified the ubiquitin ligases Seven In Absentia Homolog (SIAH)-1 and SIAH2 as binding partners of ... [more]
Biochem. Biophys. Res. Commun. Apr. 19, 2013; 433(4);390-5 [Pubmed: 23500468]
Throughput
- Low Throughput
Curated By
- BioGRID