BAIT
BAG3
BAG-3, BIS, CAIR-1, MFM6
BCL2-associated athanogene 3
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
BDKRB2
B2R, BK-2, BK2, BKR2, BRB2
bradykinin receptor B2
GO Process (10)
GO Function (6)
GO Component (3)
Gene Ontology Biological Process
- arachidonic acid secretion [IDA]
- blood circulation [NAS]
- cell surface receptor signaling pathway [TAS]
- inflammatory response [IC]
- metabolic process [TAS]
- positive regulation of cytosolic calcium ion concentration [TAS]
- regulation of vascular permeability [IC]
- regulation of vasoconstriction [IC]
- smooth muscle contraction [IC]
- transmembrane receptor protein tyrosine kinase signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-Luminescence
An interaction is inferred when a bait protein, tagged with luciferase, is enzymatically detected in immunoprecipitates of the prey protein as light emission. The prey protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag.
Publication
BAG3 Interactome Analysis Reveals a New Role in Modulating Proteasome Activity.
Bcl2-associated athanogene 3 (BAG3), a member of the BAG family of co-chaperones, plays a critical role in regulating apoptosis, development, cell motility, autophagy, and tumor metastasis, and in mediating cell adaptive responses to stressful stimuli. BAG3 carries a BAG domain, a WW domain and a proline-rich (PXXP) repeat, all of which mediate binding to different partners. To elucidate BAG3 interaction ... [more]
Mol. Cell Proteomics Jul. 03, 2013; 0(0); [Pubmed: 23824909]
Throughput
- High Throughput
Curated By
- BioGRID