BAIT
XBP1
TREB5, XBP-1, XBP2
X-box binding protein 1
GO Process (60)
GO Function (12)
GO Component (6)
Gene Ontology Biological Process
- activation of signaling protein activity involved in unfolded protein response [TAS]
- adipose tissue development [ISS]
- angiogenesis [ISS]
- cell growth [IDA]
- cellular protein metabolic process [TAS]
- cellular response to amino acid stimulus [ISS]
- cellular response to fluid shear stress [IDA]
- cellular response to fructose stimulus [ISS]
- cellular response to glucose starvation [ISS]
- cellular response to glucose stimulus [ISS]
- cellular response to insulin stimulus [ISS]
- cellular response to interleukin-4 [ISS]
- cellular response to laminar fluid shear stress [IDA]
- cellular response to lipopolysaccharide [IDA]
- cellular response to nutrient [ISS]
- cellular response to oxidative stress [IDA]
- cellular response to peptide hormone stimulus [ISS]
- cellular response to vascular endothelial growth factor stimulus [IDA]
- cellular triglyceride homeostasis [ISS]
- cholesterol homeostasis [ISS]
- endoplasmic reticulum unfolded protein response [ISS, TAS]
- endothelial cell proliferation [IDA]
- fatty acid homeostasis [ISS]
- immune response [TAS]
- liver development [ISS]
- negative regulation of apoptotic process [ISS]
- negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [IDA]
- negative regulation of endoplasmic reticulum unfolded protein response [IDA]
- negative regulation of myotube differentiation [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- neuron development [ISS]
- phosphatidylinositol 3-kinase signaling [IDA]
- positive regulation of B cell differentiation [IDA]
- positive regulation of MHC class II biosynthetic process [IMP]
- positive regulation of T cell differentiation [IDA]
- positive regulation of TOR signaling [IMP]
- positive regulation of autophagy [IDA]
- positive regulation of endoplasmic reticulum unfolded protein response [IMP]
- positive regulation of endothelial cell apoptotic process [IDA]
- positive regulation of fat cell differentiation [ISS]
- positive regulation of hepatocyte proliferation [ISS]
- positive regulation of histone methylation [IDA]
- positive regulation of immunoglobulin production [IDA]
- positive regulation of immunoglobulin secretion [ISS]
- positive regulation of interleukin-6 secretion [ISS]
- positive regulation of lactation [ISS]
- positive regulation of plasma cell differentiation [IDA]
- positive regulation of protein acetylation [IDA]
- positive regulation of protein phosphorylation [IDA]
- positive regulation of transcription factor import into nucleus [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP, ISS]
- positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [IDA, ISS]
- protein destabilization [IDA, IMP]
- regulation of protein stability [IDA]
- response to endoplasmic reticulum stress [IDA]
- response to insulin-like growth factor stimulus [ISS]
- sterol homeostasis [ISS]
- transcription from RNA polymerase II promoter [ISS]
- ubiquitin-dependent protein catabolic process [ISS]
- vascular endothelial growth factor receptor signaling pathway [IDA]
Gene Ontology Molecular Function- DNA binding [TAS]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- chromatin DNA binding [IDA]
- core promoter binding [ISS]
- enhancer sequence-specific DNA binding [IDA]
- protease binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [IDA]
- protein kinase binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription regulatory region DNA binding [IDA]
- ubiquitin protein ligase binding [IPI]
- DNA binding [TAS]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- chromatin DNA binding [IDA]
- core promoter binding [ISS]
- enhancer sequence-specific DNA binding [IDA]
- protease binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [IDA]
- protein kinase binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription regulatory region DNA binding [IDA]
- ubiquitin protein ligase binding [IPI]
Gene Ontology Cellular Component
Homo sapiens
PREY
ATF6B
CREB-RP, CREBL1, G13, DADB-220I18.4
activating transcription factor 6 beta
GO Process (2)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
FRET
An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins.
Publication
Networks of bZIP protein-protein interactions diversified over a billion years of evolution.
Differences in biomolecular sequence and function underlie dramatic ranges of appearance and behavior among species. We studied the basic region-leucine zipper (bZIP) transcription factors and quantified bZIP dimerization networks for five metazoan and two single-cell species, measuring interactions in vitro for 2891 protein pairs. Metazoans have a higher proportion of heteromeric bZIP interactions and more network complexity than the single-cell ... [more]
Science May. 10, 2013; 340(6133);730-4 [Pubmed: 23661758]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ATF6B XBP1 | FRET FRET An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins. | High | - | BioGRID | - |
Curated By
- BioGRID