SPBC2G2.14, SPBC2G2.14
mitotic chromosome segregation protein Csi1
GO Process (2)
GO Function (1)
GO Component (4)
Schizosaccharomyces pombe (972h)


DASH complex subunit Duo1
GO Process (2)
GO Function (0)
GO Component (1)

Gene Ontology Cellular Component

Schizosaccharomyces pombe (972h)

Synthetic Lethality

A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.


Csi1 links centromeres to the nuclear envelope for centromere clustering.

Hou H, Zhou Z, Wang Y, Wang J, Kallgren SP, Kurchuk T, Miller EA, Chang F, Jia S

In the fission yeast Schizosaccharomyces pombe, the centromeres of each chromosome are clustered together and attached to the nuclear envelope near the site of the spindle pole body during interphase. The mechanism and functional importance of this arrangement of chromosomes are poorly understood. In this paper, we identified a novel nuclear protein, Csi1, that localized to the site of centromere ... [more]

J. Cell Biol. Nov. 26, 2012; 199(5);735-44 [Pubmed: 23166349]


  • Low Throughput

Ontology Terms

  • phenotype: inviable (APO:0000112)

Curated By