CDC25
Gene Ontology Biological Process
- mitotic DNA replication checkpoint [IMP]
- peptidyl-tyrosine dephosphorylation involved in activation of protein kinase activity [IDA]
- positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle [IMP]
- regulation of G2/M transition of mitotic cell cycle [IMP]
- regulation of cell size [NAS]
- signal transduction involved in intra-S DNA damage checkpoint [IMP]
Gene Ontology Molecular Function
STY1
Gene Ontology Biological Process
- G1 cell cycle arrest in response to nitrogen starvation [IMP]
- G1 to G0 transition [IMP]
- MAPK cascade in response to starvation [IMP]
- MAPK cascade involved in osmosensory signaling pathway [IDA, IMP]
- cellular response to cation stress [IGI]
- cellular response to nitrogen starvation [IMP]
- mRNA export from nucleus in response to heat stress [IMP]
- mitotic cell cycle arrest in response to nitrogen starvation [IMP]
- positive regulation of G2/M transition of mitotic cell cycle [IMP]
- positive regulation of transcription factor import into nucleus in response to oxidative stress [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [IMP]
- regulation of DNA binding [IDA]
- regulation of cAMP-mediated signaling [IMP]
- regulation of cAMP-mediated signaling by regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of cell shape involved in G1 to G0 transition [IMP]
- regulation of chromatin assembly [IMP]
- regulation of chromatin disassembly [IMP]
- regulation of histone acetylation [IMP]
- regulation of mRNA stability involved in cellular response to UV [IMP]
- regulation of meiotic cell cycle [IMP]
- regulation of reciprocal meiotic recombination [IMP]
- regulation of translation in response to nitrogen starvation [IDA]
- regulation of translation in response to osmotic stress [IDA, IMP]
- regulation of translation in response to oxidative stress [IDA, IMP]
- stress granule assembly [IMP]
- stress granule disassembly [IMP]
- stress-activated MAPK cascade [IMP]
Gene Ontology Molecular Function
Dosage Rescue
A genetic interaction is inferred when over expression or increased dosage of one gene rescues the lethality or growth defect of a strain that is mutated or deleted for another gene.
Publication
Stress signal, mediated by a Hog1-like MAP kinase, controls sexual development in fission yeast.
We identified the phh1+ gene that encodes a MAP kinase as the effector of Wis1 MAP kinase kinase in fission yeast, which is highly homologous with HOG1 of S. cerevisiae. Heterothalic phh1 dsiruptant is phenotypically indistinguishable from wis1 deletion mutant, both displaying the same extent of partial sterility and enhanced sensitivity to a variety of stress. In phh1 disruptant, nitrogen ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: vegetative growth (APO:0000106)
- phenotype: heat sensitivity (APO:0000147)
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
CDC25 STY1 | Dosage Growth Defect Dosage Growth Defect A genetic interaction is inferred when over expression or increased dosage of one gene causes a growth defect in a strain that is mutated or deleted for another gene. | Low | - | BioGRID | 2609088 | |
CDC25 STY1 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | PomBase | - | |
STY1 CDC25 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 797454 | |
CDC25 STY1 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | PomBase | - |