BAIT

PCTP

PC-TP, STARD2
phosphatidylcholine transfer protein
GO Process (2)
GO Function (2)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Homo sapiens
PREY

ACOT13

PNAS-27, THEM2, HT012
acyl-CoA thioesterase 13
GO Process (2)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2.

Kanno K, Wu MK, Agate DS, Fanelli BJ, Wagle N, Scapa EF, Ukomadu C, Cohen DE

The Star (steroidogenic acute regulatory protein)-related transfer (START) domain superfamily is characterized by a distinctive lipid-binding motif. START domains typically reside in multidomain proteins, suggesting their function as lipid sensors that trigger biological activities. Phosphatidylcholine transfer protein (PC-TP, also known as StarD2) is an example of a START domain minimal protein that consists only of the lipid-binding motif. PC-TP, which ... [more]

J. Biol. Chem. Oct. 19, 2007; 282(42);30728-36 [Pubmed: 17704541]

Throughput

  • Low Throughput

Additional Notes

  • data not shown

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
PCTP ACOT13
Affinity Capture-Western
Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Low-BioGRID
886848

Curated By

  • BioGRID