BAIT
AKT2
HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA
v-akt murine thymoma viral oncogene homolog 2
GO Process (19)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- cellular protein modification process [TAS]
- cellular response to insulin stimulus [IMP]
- fat cell differentiation [TAS]
- insulin receptor signaling pathway [IMP, TAS]
- intracellular protein transmembrane transport [ISS]
- mammary gland epithelial cell differentiation [TAS]
- membrane organization [TAS]
- negative regulation of plasma membrane long-chain fatty acid transport [IMP]
- positive regulation of cell motility [IMP]
- positive regulation of fatty acid beta-oxidation [IMP]
- positive regulation of glucose import [IMP]
- positive regulation of glucose metabolic process [IMP]
- positive regulation of glycogen biosynthetic process [IMP]
- positive regulation of protein phosphorylation [ISS]
- positive regulation of protein targeting to membrane [ISS]
- positive regulation of vesicle fusion [ISS]
- regulation of cell cycle arrest [TAS]
- regulation of cell migration [TAS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell cortex [ISS]
- cytosol [TAS]
- nucleus [IDA, TAS]
- plasma membrane [ISS, TAS]
- ruffle membrane [ISS]
Homo sapiens
PREY
APOB
FLDB, LDLCQ4
apolipoprotein B
GO Process (17)
GO Function (6)
GO Component (22)
Gene Ontology Biological Process
- blood coagulation [TAS]
- cholesterol homeostasis [IMP]
- cholesterol metabolic process [IMP]
- cholesterol transport [IMP]
- leukocyte migration [TAS]
- lipoprotein metabolic process [TAS]
- low-density lipoprotein particle clearance [IMP]
- low-density lipoprotein particle remodeling [IMP]
- phototransduction, visible light [TAS]
- positive regulation of cholesterol storage [IDA]
- positive regulation of lipid storage [IDA]
- positive regulation of macrophage derived foam cell differentiation [IDA]
- receptor-mediated endocytosis [TAS]
- response to virus [IEP]
- retinoid metabolic process [TAS]
- small molecule metabolic process [TAS]
- very-low-density lipoprotein particle assembly [IC]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- actin cytoskeleton [IDA]
- chylomicron [IDA]
- chylomicron remnant [TAS]
- clathrin-coated endocytic vesicle membrane [TAS]
- cytoplasm [IDA]
- cytosol [TAS]
- early endosome [TAS]
- endocytic vesicle lumen [TAS]
- endoplasmic reticulum lumen [TAS]
- endoplasmic reticulum membrane [TAS]
- endosome lumen [TAS]
- endosome membrane [TAS]
- extracellular region [TAS]
- extracellular space [ISS]
- extracellular vesicular exosome [IDA]
- intermediate-density lipoprotein particle [IDA]
- intracellular membrane-bounded organelle [TAS]
- low-density lipoprotein particle [IDA]
- mature chylomicron [IDA]
- plasma membrane [IDA, TAS]
- very-low-density lipoprotein particle [IDA]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID