BAIT
DICER1
DCR1, Dicer, Dicer1e, HERNA, K12H4.8-LIKE, MNG1, RMSE2
dicer 1, ribonuclease type III
GO Process (15)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
- RNA phosphodiester bond hydrolysis [IDA]
- RNA phosphodiester bond hydrolysis, endonucleolytic [IDA, IMP]
- conversion of ds siRNA to ss siRNA [IMP]
- gene expression [TAS]
- negative regulation of Schwann cell proliferation [ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- nerve development [ISS]
- neuron projection morphogenesis [ISS]
- peripheral nervous system myelin formation [ISS]
- positive regulation of Schwann cell differentiation [ISS]
- positive regulation of myelination [ISS]
- pre-miRNA processing [IDA]
- production of miRNAs involved in gene silencing by miRNA [ISS]
- production of siRNA involved in RNA interference [IDA]
- targeting of mRNA for destruction involved in RNA interference [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
GO Process (10)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- carnitine shuttle [TAS]
- cell cycle arrest [TAS]
- cellular lipid metabolic process [TAS]
- energy reserve metabolic process [TAS]
- insulin receptor signaling pathway [TAS]
- membrane organization [TAS]
- protein phosphorylation [IDA]
- regulation of fatty acid biosynthetic process [TAS]
- signal transduction [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID