BAIT

TBXA2R

BDPLT13, TXA2-R
thromboxane A2 receptor
Homo sapiens
PREY

AAMP

angio-associated, migratory cell protein
GO Process (3)
GO Function (1)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Interaction of angio-associated migratory cell protein with the TPα and TPβ isoforms of the human thromboxane A₂ receptor.

Reid HM, Wikstroem K, Kavanagh DJ, Mulvaney EP, Kinsella BT

In humans, thromboxane (TX) A₂ signals through the TPα and TPβ isoforms of its G-protein coupled TXA₂ receptor (TP) to mediate a host of (patho)physiologic responses. Herein, angio-associated migratory cell protein (AAMP) was identified as a novel interacting partner of both TPα and TPβ through an interaction dependent on common (residues 312-328) and unique (residues 366-392 of TPβ) sequences within ... [more]

Cell. Signal. Apr. 01, 2011; 23(4);700-17 [Pubmed: 21172430]

Throughput

  • Low Throughput

Additional Notes

  • Isoforms (Uniprot IDs): P21731-2 interacts with Q13685

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
TBXA2R AAMP
Affinity Capture-Western
Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Low-BioGRID
907671
TBXA2R AAMP
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Low-BioGRID
907539

Curated By

  • BioGRID