ELM1
Gene Ontology Biological Process
- axial cellular bud site selection [TAS]
- budding cell bud growth [IMP]
- cell morphogenesis [IMP]
- cytokinesis checkpoint [TAS]
- glucose metabolic process [IGI, IMP]
- positive regulation of protein autophosphorylation [IDA, IMP]
- protein autophosphorylation [IDA, IMP]
- protein phosphorylation [IDA, IGI]
- pseudohyphal growth [IMP]
- response to drug [IMP]
- response to osmotic stress [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CKS1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Dosage Growth Defect
A genetic interaction is inferred when over expression or increased dosage of one gene causes a growth defect in a strain that is mutated or deleted for another gene.
Publication
Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs.
A combinatorial genetic perturbation strategy was applied to interrogate the yeast kinome on a genome-wide scale. We assessed the global effects of gene overexpression or gene deletion to map an integrated genetic interaction network of synthetic dosage lethal (SDL) and loss-of-function genetic interactions (GIs) for 92 kinases, producing a meta-network of 8700 GIs enriched for pathways known to be regulated ... [more]
Quantitative Score
- -0.542 [SGA Score]
Throughput
- High Throughput
Ontology Terms
- phenotype: vegetative growth (APO:0000106)
- phenotype: colony size (APO:0000063)
Additional Notes
- score threshold >=0.2=<
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ELM1 CKS1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.2084 | BioGRID | 2053492 | |
| CKS1 ELM1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.1824 | BioGRID | 1961446 | |
| ELM1 CKS1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -10.9652 | BioGRID | 322180 |
Curated By
- BioGRID