RGD1
Gene Ontology Biological Process
Gene Ontology Molecular Function- Rho GTPase activator activity [IDA, IGI]
- phosphatidylinositol-3,5-bisphosphate binding [IDA, IMP]
- phosphatidylinositol-3-phosphate binding [IDA, IMP]
- phosphatidylinositol-4,5-bisphosphate binding [IDA]
- phosphatidylinositol-4-phosphate binding [IDA, IMP]
- phosphatidylinositol-5-phosphate binding [IDA, IMP]
- Rho GTPase activator activity [IDA, IGI]
- phosphatidylinositol-3,5-bisphosphate binding [IDA, IMP]
- phosphatidylinositol-3-phosphate binding [IDA, IMP]
- phosphatidylinositol-4,5-bisphosphate binding [IDA]
- phosphatidylinositol-4-phosphate binding [IDA, IMP]
- phosphatidylinositol-5-phosphate binding [IDA, IMP]
Gene Ontology Cellular Component
ATG1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Negative Genetic
Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores.
Publication
Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs.
A combinatorial genetic perturbation strategy was applied to interrogate the yeast kinome on a genome-wide scale. We assessed the global effects of gene overexpression or gene deletion to map an integrated genetic interaction network of synthetic dosage lethal (SDL) and loss-of-function genetic interactions (GIs) for 92 kinases, producing a meta-network of 8700 GIs enriched for pathways known to be regulated ... [more]
Quantitative Score
- -0.225 [SGA Score]
Throughput
- High Throughput
Ontology Terms
- vegetative growth (APO:0000106)
- colony size (APO:0000063)
Additional Notes
- score threshold <= -0.12, interaction detected by Synthetic Genetic Array (SGA)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RGD1 ATG1 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - | |
| ATG1 RGD1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.225 | BioGRID | 379197 | |
| RGD1 ATG1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.225 | BioGRID | 360033 | |
| RGD1 ATG1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.2629 | BioGRID | 2084085 |
Curated By
- BioGRID