TJP2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
KIF14
Gene Ontology Biological Process
- ATP catabolic process [IBA, ISS]
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [IMP]
- activation of protein kinase activity [IMP]
- cell proliferation in forebrain [ISS]
- cerebellar Purkinje cell layer structural organization [ISS]
- cerebellar cortex development [ISS]
- cerebellar granular layer structural organization [ISS]
- cerebral cortex development [ISS]
- cytoskeleton-dependent intracellular transport [IBA]
- establishment of protein localization [IDA]
- hippocampus development [ISS]
- microtubule depolymerization [ISS]
- microtubule-based movement [IBA]
- mitotic cell cycle process [IMP]
- mitotic metaphase plate congression [IMP]
- negative regulation of apoptotic process [IMP]
- negative regulation of integrin activation [IMP]
- negative regulation of neuron apoptotic process [ISS]
- olfactory bulb development [ISS]
- positive regulation of cell proliferation [IDA, IMP]
- positive regulation of cytokinesis [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IMP]
- regulation of G1/S transition of mitotic cell cycle [IMP]
- regulation of G2/M transition of mitotic cell cycle [IMP]
- regulation of Rap protein signal transduction [IMP]
- regulation of cell adhesion [IMP]
- regulation of cell growth [IMP]
- regulation of cell migration [IMP]
- regulation of myelination [ISS]
- regulation of neuron apoptotic process [ISS]
- response to docetaxel trihydrate [IMP]
- substrate adhesion-dependent cell spreading [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Protein interaction network of the Mammalian hippo pathway reveals mechanisms of kinase-phosphatase interactions.
The Hippo pathway regulates organ size and tissue homeostasis in response to multiple stimuli, including cell density and mechanotransduction. Pharmacological inhibition of phosphatases can also stimulate Hippo signaling in cell culture. We defined the Hippo protein-protein interaction network with and without inhibition of serine and threonine phosphatases by okadaic acid. We identified 749 protein interactions, including 599 previously unrecognized interactions, ... [more]
Quantitative Score
- 1.0 [Saint Score]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| KIF14 TJP2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - | |
| TJP2 KIF14 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 3373256 | |
| TJP2 KIF14 | Proximity Label-MS Proximity Label-MS An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods. | High | 116.44 | BioGRID | 3009453 |
Curated By
- BioGRID