BAIT

CKS1B

CKS1, PNAS-16, PNAS-18, ckshs1, RP11-307C12.6
CDC28 protein kinase regulatory subunit 1B
GO Process (4)
GO Function (1)
GO Component (1)
Homo sapiens
PREY

SSBP1

Mt-SSB, SOSS-B1, SSBP, mtSSB
single-stranded DNA binding protein 1, mitochondrial
GO Process (1)
GO Function (3)
GO Component (4)
Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

CKS proteins protect mitochondrial genome integrity by interacting with mitochondrial single-stranded DNA-binding protein.

Radulovic M, Crane E, Crawford M, Godovac-Zimmermann J, Yu VP

Cyclin-dependent kinase subunit (CKS) proteins interact with cyclin-dependent kinases (CDKs) with high affinity. Mammalian CKS1 and CKS2 bind CDK1 and CDK2 and partake in the control of cell cycle progression. We identified CKS-interacting proteins by affinity purification followed by mass spectrometry in the human lymphocytic cell line Ramos. Apart from known interactors, such as CDKs, we identified a novel CDK-dependent ... [more]

Mol. Cell Proteomics Jan. 01, 2010; 9(1);145-52 [Pubmed: 19786724]

Throughput

  • Low Throughput

Curated By

  • BioGRID