CCAR2
Gene Ontology Biological Process
- RNA splicing [IMP]
- mitochondrial fragmentation involved in apoptotic process [IDA]
- negative regulation of catalytic activity [IDA, IMP]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [IMP]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [IDA]
- positive regulation of DNA damage checkpoint [IMP]
- positive regulation of apoptotic process [IMP]
- regulation of DNA-templated transcription, elongation [IMP]
- regulation of circadian rhythm [ISS]
- regulation of protein stability [IDA]
- response to UV [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
HNRNPA1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A high-throughput approach for measuring temporal changes in the interactome.
Interactomes are often measured using affinity purification-mass spectrometry (AP-MS) or yeast two-hybrid approaches, but these methods do not provide stoichiometric or temporal information. We combine quantitative proteomics and size-exclusion chromatography to map 291 coeluting complexes. This method allows mapping of an interactome to the same depth and accuracy as AP-MS with less work and without overexpression or tagging. The use ... [more]
Throughput
- High Throughput
Ontology Terms
- cell line: hela cell (BTO:0000567) [cervical adenocarcinoma (DOID:3702)]
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
HNRNPA1 CCAR2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - | |
HNRNPA1 CCAR2 | Proximity Label-MS Proximity Label-MS An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods. | High | 18.01 | BioGRID | 2990341 |
Curated By
- BioGRID