BAIT
ATP6V1B2
ATP6B1B2, ATP6B2, HO57, VATB, VPP3, Vma2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
GO Process (7)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MSH6
GTBP, GTMBP, HNPCC5, HSAP, p160
mutS homolog 6
GO Process (15)
GO Function (16)
GO Component (7)
Gene Ontology Biological Process
- ATP catabolic process [IBA, IDA]
- DNA repair [IDA]
- determination of adult lifespan [ISS]
- intrinsic apoptotic signaling pathway [ISS]
- intrinsic apoptotic signaling pathway in response to DNA damage [IBA, ISS]
- isotype switching [IBA, ISS]
- maintenance of DNA repeat elements [IMP]
- meiotic mismatch repair [IBA, ISS]
- mismatch repair [IDA, IGI, IMP]
- negative regulation of DNA recombination [IDA]
- positive regulation of helicase activity [IDA]
- reciprocal meiotic recombination [IBA]
- response to UV [IBA, ISS]
- somatic hypermutation of immunoglobulin genes [IBA, ISS]
- somatic recombination of immunoglobulin gene segments [ISS]
Gene Ontology Molecular Function- ADP binding [IDA]
- ATP binding [IDA]
- ATPase activity [IDA]
- DNA-dependent ATPase activity [IBA]
- MutLalpha complex binding [IDA]
- double-stranded DNA binding [IDA]
- four-way junction DNA binding [IDA]
- guanine/thymine mispair binding [IDA]
- magnesium ion binding [IDA]
- methylated histone binding [IDA]
- mismatched DNA binding [IDA]
- oxidized purine DNA binding [IDA]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- single guanine insertion binding [IDA]
- single thymine insertion binding [IDA]
- ADP binding [IDA]
- ATP binding [IDA]
- ATPase activity [IDA]
- DNA-dependent ATPase activity [IBA]
- MutLalpha complex binding [IDA]
- double-stranded DNA binding [IDA]
- four-way junction DNA binding [IDA]
- guanine/thymine mispair binding [IDA]
- magnesium ion binding [IDA]
- methylated histone binding [IDA]
- mismatched DNA binding [IDA]
- oxidized purine DNA binding [IDA]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- single guanine insertion binding [IDA]
- single thymine insertion binding [IDA]
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A high-throughput approach for measuring temporal changes in the interactome.
Interactomes are often measured using affinity purification-mass spectrometry (AP-MS) or yeast two-hybrid approaches, but these methods do not provide stoichiometric or temporal information. We combine quantitative proteomics and size-exclusion chromatography to map 291 coeluting complexes. This method allows mapping of an interactome to the same depth and accuracy as AP-MS with less work and without overexpression or tagging. The use ... [more]
Nat. Methods Sep. 01, 2012; 9(9);907-9 [Pubmed: 22863883]
Throughput
- High Throughput
Ontology Terms
- cell line: hela cell (BTO:0000567) [cervical adenocarcinoma (DOID:3702)]
Curated By
- BioGRID