BAIT
DIS3
2810028N01Rik, EXOSC11, KIAA1008, RRP44, dis3p, RP11-342J4.3
DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
GO Process (11)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
- CUT catabolic process [IMP]
- RNA metabolic process [TAS]
- RNA phosphodiester bond hydrolysis, exonucleolytic [IMP]
- exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
- nucleic acid phosphodiester bond hydrolysis [IMP]
- positive regulation of GTPase activity [IDA]
- rRNA catabolic process [IMP]
- rRNA processing [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TWF1
A6, PTK9
twinfilin actin-binding protein 1
GO Process (3)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A high-throughput approach for measuring temporal changes in the interactome.
Interactomes are often measured using affinity purification-mass spectrometry (AP-MS) or yeast two-hybrid approaches, but these methods do not provide stoichiometric or temporal information. We combine quantitative proteomics and size-exclusion chromatography to map 291 coeluting complexes. This method allows mapping of an interactome to the same depth and accuracy as AP-MS with less work and without overexpression or tagging. The use ... [more]
Nat. Methods Sep. 01, 2012; 9(9);907-9 [Pubmed: 22863883]
Throughput
- High Throughput
Ontology Terms
- cell line: hela cell (BTO:0000567) [cervical adenocarcinoma (DOID:3702)]
Curated By
- BioGRID